Research Article

Nayyer Shamim, Uswa Muzzamil, Rida, Zahid Iqbal, Jannat Sohail, Aleena Ahtesham, Umama

Published on : June 2025 | Volume : 2 Issue : 1

Abstract :

Psoriasis is a common chronic illness caused by the weak immune system that impacts about 2% of everyone globally and greatly lowers quality of life (qol). This condition does not only cause discomfort but it can also cause depression, lead to isolation, and affect one’s performance at work. The study focused on analyzing how psoriasis impacts qol, depending on illness severity, treatment methods, and related social and emotional issues of patients living in Lahore, Pakistan. A case-only study was conducted at Azra Naheed Hospital and the University of Lahore Teaching Hospital, Lahore. After obtaining consent from the patients, the data were collected using a questionnaire that recorded the age, medical history, treatment received, psychological effects of the disease, and how they cope. To analyze quantitative data, R-statistical language (version 4.3) was used. Associations between where patients experienced affected areas and their qol were measured using frequencies, correlations, and logistic regression models. In patients 40 years or older, common comorbidities such as psoriatic arthritis (39%) and cardiovascular disease (34%) were more prevalent. Those patients with multiple body parts affected experienced much more emotional distress and physical discomfort. Multivariable analysis revealed that these patients had 2.6 times increased chances of emotional distress and 3.53 times increased chances of physical Discomfort (p<0.001). Problems at school and in the workplace were the most Common kinds of impact. After comparing two groups based on body parts affected, It was clear that patients with multiple body parts affected had lower social Confidence and higher emotional stress. Moderate similarity was found in the Outcomes of work-related changes and those of changes in social activities. Receiver Operating Characteristic (ROC) curves revealed that social impact was easier to Predict than other aspects of quality of life, but none of the models showed strong Ability to separate subjects. In conclusion, psoriasis has a major influence on a Person’s emotional, social, and daily functioning. Greater and deeper involvement Of the body by disease negatively impacts a person’s qol. he need for broad Evaluation tools and specific treatments that cover both health and social concerns Of patients with psoriasis is highlighted in this study.